Normalisation and Quality Control for DNA Microarray Data: Analysis of a M.tuberculosis growth curve experiment
نویسندگان
چکیده
منابع مشابه
Row Quantile Normalisation of Microarrays
Variation in tissue sample preparation leads to variation across the Transcriptome not just between experiments but to between individual microarrays. Normalisation is essential before data from different arrays can be compared. Quantile normalisation can be used to force data from a single GeneChip to take a given distribution. However quantile normalisation can be blind to the consistent spat...
متن کاملDNA microarray normalisation, PCA and a related latent variable model
We study the effects of DNA microarray data pre-processing and normalisation. Our main methodology involves the comparison of results produced by a Principal Components Analysis under different treatments. We compare different normalisation strategies and parameterisations, and we consider the effects of choosing different noise cut-offs. We compare results using two publicly available Affymetr...
متن کاملبه کارگیری روشهای خوشهبندی در ریزآرایه DNA
Background: Microarray DNA technology has paved the way for investigators to expressed thousands of genes in a short time. Analysis of this big amount of raw data includes normalization, clustering and classification. The present study surveys the application of clustering technique in microarray DNA analysis. Materials and methods: We analyzed data of Van’t Veer et al study dealing with BRCA1...
متن کاملLetter to editor " Applying High-quality DNA Melting Curve Analysis in Identifying Staphylococcus aureus and Methicillin-resistant Strains "
Letter to editor " Applying High-quality DNA Melting Curve Analysis in Identifying Staphylococcus aureus and Methicillin-resistant Strains " Ramezan Ali Ataee Professor, Department of Medical Microbiology, Faculty of Medicine, Hospital Research Development Committee, Applied Microbiology Research Center, System Biology, Poisoning Institute, Baqiyatallah University of Medical Sciences, T...
متن کاملPredicting CpG Islands and DNA Methlation in the Cow Genome Using DNA Microarray Meta-Analysis and Genome Wide Scanning
DNA methylation is a type of epigenetic changes that directly affects DNA. In mammals, DNA methylation is essential for fetal development and stem cell differentiation and this phenomenon essentially occurs within the CpG islands. In this study, two methods were used to study the DNA methylation profile of cow genome. In the first method, the DNA methylation profile of the differentially expres...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2003